Diabetic retinopathy and stroke – How are they linked?

Diabetic retinopathy represents an independent
risk factor for stroke, suggesting that microvascular pathology plays a
role.
A recent study followed patients with diabetes to determine the
prevalence of disease affecting flow of blood to the brain. Two centers, in
Milan and Belfast, enrolled a total of 516 eyes from 258 diabetic patients.
Ultrawide scale color fundus photography was graded for
severity of diabetic retinopathy and predominant presence of
peripheral damage (>50% of damage). OCT-A was obtained in 252 eyes, which
were examined for perimeter, area and circularity of the avascular zone and
vessel density, perfusion density, dimension in superficial,
intermediate and deep capillary plexuses.


Their findings that perfusion density and interstitial
vessel density of the plexus were associated with stroke may be indicative
that diabetic patients with a history of stroke have major
alterations in the microcirculation of the retina. As the researchers explain,
retinal vascular lesions likely reflect similar
pathological processes in the cerebral microcirculation due to the retina
and brain sharing a similar embryological origin, anatomical and
physiological characteristics.

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https://www.reviewofoptometry.com/news/article/diabetic-retinopathy-severity-linked-to-stroke

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